I feel privileged to practice at Harborview and teach in the UW School of Medicine. I am fortunate to get to work on a daily basis with such dedicated and talented colleagues, students, and collaborators to bring the highest quality of clinical care, compassion, and innovation to the communities we serve.


Mark Whipple, M.D., M.S., graduated from the University of Washington School of Medicine and completed his otolaryngology-head & neck surgery training at the University of Illinois in Chicago. He practiced in his home town of Fairbanks, Alaska, for several years before receiving graduate training in biomedical informatics in the Harvard-MIT program. He then joined the Department of Otolaryngology-Head and Neck Surgery at UW in 2001. He has served as chief of Oto-HNS at Harborview Medical Center since 2007. In addition to his clinical activities, Dr. Whipple teaches in the UW medical school and does research in biomedical informatics.


Undergraduate Education: Stanford University, Palo Alto, Cal., 1987

Medical School: University of Washington, 1991

Internship: University of Illinois, Chicago, 1992

Residency: University of Illinois, Chicago, 1996

Fellowship: Boston Children's Hospital, Research Fellowship in Bioinformatics, 2001

Other Training: Master's in Medical Informatics, Massachusetts Institute of Technology, 2001

Board Certification: Otolaryngology, 1997

Memberships: Fellow, American College of Surgeons

Awards and honors 

2009: Harborview CARES Award for Service Excellence
2009: American Academy of Otolaryngology-Head & Neck Surgery Honor Award
2007: University of Washington School of Medicine Service Excellence Award
2002: UW Dept of Oto/HNS Trachy Award for Contributions to Resident Research
1995: Chicago Laryngologic and Otologic Society, Lederer-Pierce Prize for Resident Research
1991: Graduation with Honors, University of Washington School of Medicine
1990: Alpha Omega Alpha, University of Washington School of Medicine
1987: Graduation with Distinction, Stanford University

Academic interests 


Dr. Whipple practices all aspects of adult otolaryngology with particular interest in the surgical management of craniofacial trauma.



Dr. Whipple's research has focused on informatics approaches to better understand the development and metastasis of head and neck neoplasms. Specific efforts include developing algorithms to identify tumor biomarkers, genomic and micro-RNA analyses, and computational models of tumor spread.


Recent Publications

Wu S, Law A, Whipple ME. A Bayesian Network Model of Head and Neck Squamous Cell Carcinoma Incorporating Gene Expression Profiles., Stud Health Technol Inform 2017 ; 245634-638

Li Y, Bly RA, Harbison RA, Humphreys IM, Whipple ME, Hannaford B, Moe KS. Anatomical Region Segmentation for Objective Surgical Skill Assessment with Operating Room Motion Data., J Neurol Surg B Skull Base 2017 Dec; 78(6):490-496

Jung H, Law A, Grunblatt E, Wang LL, Kusano A, Mejino JL, Whipple ME. Development of a Novel Markov Chain Model for the Prediction of Head and Neck Squamous Cell Carcinoma Dissemination., AMIA Annu Symp Proc 2016 ; 20161832-1839

Patel SA, Berens AM, Devarajan K, Whipple ME, Moe KS. Evaluation of a Minimally Disruptive Treatment Protocol for Frontal Sinus Fractures., JAMA Facial Plast Surg 2017 May; 19(3):225-231

Strub GM, Kirsh AL, Whipple ME, Kuo WP, Keller RB, Kapur RP, Majesky MW, Perkins JA. Endothelial and circulating C19MC microRNAs are biomarkers of infantile hemangioma., JCI Insight 2016 Sep; 1(14):e88856