Resident Research and Scholarly Activities

2016 – 2017

• PUBLICATIONS

Akkina, S. R., Novis, S. J., Keshavarzi, N. R. and Pynnonen, M. A. (2016), Academic institution pilot study shows far fewer diagnoses of sinusitis than reported nationally. Laryngoscope Investigative Otolaryngology. 2016 Oct; 1: 124–129.

Patel SA, Liu JL, Murakami CS, Berg D, Akkina SR, Bhrany AD. Complication Rates in Delayed Reconstruction of the Head and Neck After Mohs Micrographic Surgery. JAMA Facial Plast Surg. 2016 Sept; 18(5):340-346.

Raudaschl PF, Zaffino P, Sharp GC, Spadea MF, Chen A, Dawant BM, Albrecht T, Gass T, Langguth C, Lüthi M, Jung F, Knapp O, Wesarg S, Mannion-Haworth R, Bowes M, Ashman A, Guillard G, Brett A, Vincent G, Orbes-Arteaga M, Cárdenas-Peña D, Castellanos-Dominguez G, Aghdasi N, Li Y, Berens A, Moe K, Hannaford B, Schubert R, Fritscher KD. Evaluation of Segmentation Methods on Head and Neck CT: Auto-Segmentation Challenge 2015., Med Phys 2017 Mar

Patel SA, Berens AM, Devarajan K, Whipple ME, Moe KS. Evaluation of a Minimally Disruptive Treatment Protocol for Frontal Sinus Fractures., JAMA Facial Plast Surg 2017 Feb

Berens AM, Davis GE, Moe KS. Transorbital endoscopic identification of supernumerary ethmoid arteries., Allergy Rhinol (Providence) 2016 Jan; 7(3):144-146

Berens AM, Newman S, Bhrany AD, Murakami C, Sie KC, Zopf DA. Computer-Aided Design and 3D Printing to Produce a Costal Cartilage Model for Simulation of Auricular Reconstruction., Otolaryngol Head Neck Surg 2016 Aug; 155(2):356-9

Davis RJ, Moore EC, Clavijo PE, Friedman J, Cash HA, Chen Z, Silvin C, Van Waes C, Allen CT. Anti-PD-L1 efficacy can be enhanced by inhibition of myeloid derived suppressor cells with a selective inhibitor of PI3Kδ/γ., Cancer Res. 2017 Mar

Moore EC, Clavijo PE, Davis R, Cash HA, Van Waes C, et al. Established T-cell inflamed tumors rejected after adaptive resistance was reversed by combination STING activation and PD-1-pathway blockade. Cancer Immunol Res. 2016 Nov 7;PubMed PMID: 27821498.

Shah S, Caruso A, Cash H, Waes CV, Allen CT. Pools of programmed death-ligand within the oral cavity tumor microenvironment: Variable alteration by targeted therapies. Head Neck. 2016 Aug;38(8):1176-86. PubMed PMID: 27061215.

Moore EC, Cash HA, Caruso AM, Uppaluri R, Hodge JW, et al. Enhanced Tumor Control with Combination mTOR and PD-L1 Inhibition in Syngeneic Oral Cavity Cancers. Cancer Immunol Res. 2016 Jul;4(7):611-20. PubMed PMID: 27076449; NIHMSID: NIHMS779504; PubMed Central PMCID: PMC4930724.

Harbison RABerens AM, Li Y, Bly RA, Hannaford B, Moe KS. Region-Specific Objective Signatures of Endoscopic Surgical Instrument Motion: A Cadaveric Exploratory Analysis., J Neurol Surg B Skull Base 2017 Feb; 78(1):99-104

Harbison RA, Shan X, Douglas Z, Bevans S, Li Y, Moe KS, Futran N, Houlton JJ. Navigation Guidance During Free Flap Mandibular Reconstruction: A Cadaveric Trial. JAMA Otolaryngol Head Neck Surg. Published online November 17, 2016. 

Harbison RA, Johnson K, Miller C, Sardesai M, Davis GE. Face, Content, and Construct Validation of a Low-Cost, Non-Biologic Sinus Surgery Task Trainer. Submitted and accepted for publication. International Forum of Allergy & Rhinology.

Jáuregui EJ, Akil O, Acevedo C, Hall-Glenn F, Tsai BS, Bale HA, Liebenberg E, Humphrey MB, Ritchie RO, Lustig LR, Alliston T. Parallel mechanisms suppress cochlear bone remodeling to protect hearing. Bone. 2016 Aug; 89:7-15. (Cover Art)

Jáuregui EJ, Tummala N, Seth R, Arron S, Neuhaus I, Yu S, Grekin R, Knott PD. Comparison of W-Plasty vs Traditional Straight-Line Techniques for Primary Paramedian Forehead Flap Donor Site Closure. JAMA Facial Plast Surg. 2016 Jul 1;18(4):258-62 (Oral Presentation at the American Academy of Facial Plastic and Reconstructive Surgery)

Jáuregui, EJ; Kiringoda, R; Ryan, WR;  Eisele, DW; Chang, JL. Chronic Parotitis With Multiple Calcifications: Clinical and Sialendoscopic Findings. Laryngoscope, 2016. In press.  

Lee VS, Humphreys IM, Purcell PL, Davis GE. Manuka honey sinus irrigation for the treatment of chronic rhinosinusitis: a randomized controlled trial. Int Forum Allergy Rhinol. In press.

Lee VS, Evans KN, Perez FA, Oron AP, Perkins JA. Upper Airway Computed Tomography Measures and Receipt of Tracheotomy in Infants With Robin Sequence. JAMA Otolaryngol Head Neck Surg. August 2016;142(8):750-757.

Miller C, Purcell PL, Dahl JP, Johnson KJ, Horn DL, Chen ML, Chan DK, et al. Clinically Small Tonsils are Typically Not Obstructive in Children During Drug Induced Sleep Endoscopy. Accepted for Publication. Laryngoscope 11/10/16

Purcell PL, Jones-Goodrich R, Wisneski M, Edwards TC, Sie KC. Hearing devices for children with unilateral hearing loss: Patient- and parent-reported perspectives. Int J Pediatr Otorhinolaryngol. 2016 Nov; 90: 43-48.

Dahl JP, Purcell PL, Parikh SR, Inglis AF. Endoscopic posterior cricoid split with costal cartilage graft: A fifteen-year experience. Laryngoscope. 2016 Jul.

Strub GM, Kirsh AL, Whipple ME, Kuo WP, Keller RB, Kapur RP, Majesky MW, Perkins JA. Endothelial and circulating C19MC microRNAs are biomarkers of infantile hemangioma., JCI Insight 2016 Sep; 1(14):e88856 

• PRESENTATIONS

Akkina SR, Cheng CC, Horn DL, Chen ML, Parikh SR. Sleep Endoscopy in children with Down’s syndrome. American Society of Pediatric Otolaryngology Annual Meeting, Austin, Texas. May 18 - 21, 2017. Presentation.

RA Harbison, C Miller, M Sardesai, GE Davis, and K Johnson. “A modular low-cost otolaryngology task trainer.” American Academy of Otolaryngology – Head and Neck Surgery Annual Meeting, San Diego, California. September 18-21st, 2016. Simulation Demonstration.

RA Harbison, XF Shan, Z Douglas, S Bevans, Y Li, AM Berens, R Bly, Y Li, B Hannaford, KS Moe, ND Futran, JJ Houlton. "Navigation guidance improves free-flap mandible reconstruction: a cadaveric trial." American Head and Neck Society, 9th International Conference on Head and Neck Cancer, Seattle, Washington. July 16-19th, 2016. Poster.

RA Harbison, Y Li, AM Berens, N Aghdasi, B Hannaford, KS Moe. "An automated methodology for assessing anatomy-specific instrument motion during endoscopic endonasal skull base surgery." AHNS 9th International Conference on Head and Neck Cancer, Seattle, Washington. July 16-19th, 2016. Poster.

Kirkham EM.  Oral presentation:  “Snoring is associated with high-risk carotid plaques”.  Sep 21, 2016.  Meeting of the Acadmy of Otolaryngology 2016.  San Diego, California. 

• AWARDS

Harbison RA, 2016-2017 Principal Investigator, “Skills Transfer to Sinus Surgery via a Low-Cost Simulation-Based Curriculum”, American Rhinologic Society, Centralized Otolaryngology Research Effort, American Academy of Otolaryngology - Head & Neck Surgery Foundation, $7,709.

Harbison RA, 2016 AAO-HNS/F Resident Leadership Grant.

Jara, SM. The association between obstructive sleep apnea and cancer in VA patients. Primary Investigator (Mentor: Edward Weaver). The AAO-HNSF Rande H. Lazar Health Services Research Grant (CORE). $10,000. 07/01/2016 – 06/30/2017.

Lee, V. Recipient, 8th biennial Western States Rhinology Resident Travel Grant, Sonoma, CA, October 13-15, 2016.

2015 – 2016

• PUBLICATIONS

Sarah J. Novis, Sarah R. Akkina, Shana Lynn, Hayley E. Kern, Nahid R. Keshavarzi, Melissa A. Pynnonen. A Diagnostic Dilemma: Chronic Sinusitis Diagnosed by Non-Otolaryngologists. Int Forum Allergy Rhinol. 2016 May; 6(5): 486–490. 

Melissa A Pynnonen, Shana Lynn, Hayley E Kern, Sarah J Novis, Sarah R Akkina, Nahid R Keshavarzi, Matthew M. Davis. Diagnosis and treatment of acute sinusitis in the primary care setting: a retrospective cohort. Laryngoscope. 2015 Oct; 125(10): 2266–2272. 

Kirkham EM, Edwards TC, Weaver EM, Balakrishnan K, Perkins JA.  The Lymphatic Malformation Function (LMF) Instrument.  Otolaryngology – Head and Neck Surgery.  2015 Oct;153(4):656-62.

Kirkham EM, Heckbert SR, Weaver EM.  “Relationship Between Clinical and Polysomnography Measures Corrected for CPAP Use.”  Journal of Clinical Sleep Medicine.  Nov 15;11(11):1305-12.

Mayerhoff RM, Kuo CY, Meyer TK. A Novel Approach to the Challenging Injection Laryngoplasty. Accepted to Annals of Otology, Rhinology & Laryngology, September 2015.

Lee VS, Gold RM, Parikh SR. Short-term quality of life outcomes following pediatric septoplasty. Acta Oto-Laryngologica. In press.

Lee VS, Davis GE. Culture-directed topical antibiotic treatment for chronic rhinosinusitis. American Journal of Rhinology and Allergy. In press.

Lee VS, Humphreys IM, Purcell PL, Davis GE. Manuka honey sinus irrigation for the treatment of chronic rhinosinusitis: a randomized controlled trial.  Podium Presentation. American Rhinologic Society at AAO-HNSF Annual Meeting, San Diego, CA, September 17, 2016.

Mercado-Pimentel ME, Miller C, Rolph DN, Villalobos EF, Dunn AM, Mohan PM, Igarashi S, Liu X, Yrun-Duffy M, Patel NK, Read CM, Francis RH, Lane AI, Murugesh S, Jacob A. Inhibiting p21-Activated Kinase Induces Cell Death in Vestibular Schwannoma and Meningioma via Mitotic Catastrophe. Otol Neurotol. 2017 Jan;38(1):139-146. PubMed PMID: 27755359; PubMed Central PMCID: PMC5154791.

Dahl JP, Miller C, Purcell PL, Zopf DA, Johnson K, Horn DL, et al. Airway Obstruction during Drug-Induced Sleep Endoscopy Correlates with Apnea-Hypopneal Index and Oxygen Nadir in Children. Otolaryngology -- Head and Neck Surgery 0194599816653113, first published on June 14, 2016.

Mitchell RM and Parikh SR. Hemostasis in Tonsillectomy, In: Hemostasis in Head and Neck Surgery. Otolaryngology Clinics of North America. 2016 June;49(3), 615-626.

Mitchell, R. M., Mendez, E., Schmitt, N. C., Bhrany, A. D., & Futran, N. D. (2015). Antibiotic prophylaxis in patients undergoing head and neck free flap reconstruction. JAMA Otolaryngology - Head and Neck Surgery, 141(12), 1096-1103. DOI: 10.1001/jamaoto.2015.0513.

Qualls HE, Mitchell RM, Deubner H, Moe KS, Sardesai MG. Nasal Angiosarcoma Metastatic to the Larynx: Case Report and Systematic Review of the Literature. Head Neck 2016 May; 38(5):E99-104

Noble AR, Greskovich JF, Han J, Reddy CA, Nwizu TI, Khan MF, Scharpf J, Adelstein DJ, Burkey BB, Koyfman SA. Risk Factors Associated with Disease Recurrence in Patients with Stage III/IV Squamous Cell Carcinoma of the Oral Cavity Treated with Surgery and Postoperative Radiotherapy. 2016 Anticancer Res. Feb;36(2):785-92.

Bledsoe TJ, Noble AR, Reddy CA, Burkey BB, Greskovich JF, Nwizu T, Adelstein DJ, Saxton JP, Koyfman SA. Split-Course Accelerated Hypofractionated Radiotherapy (SCAHRT): A Safe and Effective Option for Head and Neck Cancer in the Elderly or Infirm. Anticancer Res. 2016 Mar;36(3):933-9.

Purcell PL, Shinn JR, Davis GE, Sie KC. Children with unilateral hearing loss may have lower intelligence quotient scores: A meta-analysis. Laryngoscope. 2016 Mar; 126(3): 746-54. 

Purcell PL, Iwata AJ, Phillips GS, Paladin AM, Sie KCY, Horn DL. Bony cochlear nerve canal stenosis and speech discrimination in pediatric unilateral hearing loss. Laryngoscope. 2015 Jul;125(7):1691-6.

Billings KR, Qureshi H, Gouveia C, Ittner C, Hoff SR. Management of hearing loss and the normal ear in cases of unilateral Microtia with aural atresia., Laryngoscope 2016 Jun; 126(6):1470-4

Gouveia CJ, Qureshi HA, Kern RC, Shintani Smith S. National Institutes of Health Funding for Obstructive Sleep Apnea: An Opportunity for Otolaryngologists., Otolaryngol Head Neck Surg 2015 Oct; 153(4):671-8

Lemieux A, Kedarisetty S, Raju S, Orosco R, Coffey C. Lymph Node Yield as a Predictor of Survival in Pathologically Node Negative Oral Cavity Carcinoma. Otolaryngology -- Head and Neck Surgery. Accepted November 2015.

Hussain T, Mastrodimos MB, Raju SC, Glasgow HL, Whitney M, Friedman B, Moore JD, Kleinfeld D, Steinbach P, Messer K, Pu M, Tsien RY, Nguyen QT. Fluorescently labeled peptide increases identification of degenerated facial nerve branches during surgery and improves functional outcome., PLoS ONE 2015 ; 10(3):e0119600

Raju SC, Hauff SJ, Lemieux AJ, Orosco RK, Gross AM, Nguyen LT, Savariar E, Moss W, Whitney M, Cohen EE, Lippman SM, Tsien RY, Ideker T, Advani SJ, Nguyen QT. Combined TP53 mutation/3p loss correlates with decreased radiosensitivity and increased matrix-metalloproteinase activity in head and neck carcinoma., Oral Oncol. 2015 May; 51(5):470-5

Raju S, Vazirnia A, Totri C, Hata TR. Treatment of Merkel cell carcinoma of the head and neck: a systematic review., Dermatol Surg 2014 Dec; 40(12):1273-83

Rachidi S, Sood AJ, Rumboldt T, Day TA. Intramuscular myxoma of the paraspinal muscles: A case report and systematic review of the literature., Oncol Lett 2016 Jan; 11(1):466-470

Rachidi S, Sood AJ, Patel KG, Nguyen SA, Hamilton H, Neville BW, Day TA. Melanotic Neuroectodermal Tumor of Infancy: A Systematic Review., J. Oral Maxillofac. Surg. 2015 Oct; 73(10):1946-56

Fox NF, Xiao C, Sood AJ, Lovelace TL, Nguyen SA, Sharma A, Day TA. Hyperbaric oxygen therapy for the treatment of radiation-induced xerostomia: a systematic review., Oral Surg Oral Med Oral Pathol Oral Radiol 2015 Jul; 120(1):22-8

• PRESENTATIONS

Berens A. Oral presentation: “CAD and 3D Printing for Simulation of Auricular Reconstruction.” American Academy of Otolaryngology-Head and Neck Surgery annual meeting. Dallas, TX. Sept. 2015.

RA Harbison, A Berens, Y Li, B Hannaford, KS Moe. "Objective Signatures of Endoscopic Surgical Performance." 26th Annual North American Skull Base Society meeting, Scottsdale, Arizona. February 13th, 2016. Oral presentation.

RA Harbison, R Bly, J White, R Ching, B Hannaford, K Moe. "Computer Modeling of Skull Base Endoscopic Instrument Motion and Surgical Pathway Analysis." 24th Annual North American Skull Base Society meeting, San Diego, California. February 14th, 2014. Oral presentation.

Kirkham EM, Dahl JP, Skirko JR, Kinter S, Perkins JA, Sie KC.  Perceptual speech outcomes after sphincter pharyngoplasty for velopharyngeal insuffieciency.  Poster presentation at the academy of pediatric otolaryngology meeting, May 2016, Chicago, IL

Lee VS, Davis GE. Culture-directed topical antibiotics for chronic sinusitis. Podium presentation. AAO-HNSF Annual Meeting, Dallas, TX, September 27-30, 2015.

Miller C, Purcell PL, Dahl JP, Johnson K, Horn D, Chen ML, Chan DK, Parikh SR. Does Brodsky tonsil score correlate with lateral pharyngeal wall obstruction seen on pediatric sleep endoscopy. Triological Societies Section Meeting (1/2016). Miami, FL. 

Strub, GM. Endothelial and Circulating C19MC microRNAs are Biomarkers of Infantile Hemangioma. ASPO, May 2016.

• AWARDS

Atmakuri, M. Focused Project Grant Award from the American Sleep Medicine Foundation (ASMF), December 2015

Lee VS. Manuka honey for chronic rhinosinusitis: a randomized controlled trial. Derma Sciences. $9,541 plus $20,000 worth of MEDIHONEY® product. 07/01/15 – 06/30/17.

Lee VS. Objective Imaging measures to guide Robin Sequence airway management. Primary Investigator (Mentors: Jonathan Perkins, Kelly Evans). American Society of Pediatric Otolaryngology CORE Research Grant. $20,000. 07/01/2015 – 06/30/2016.

Strub GM. First Place Poster, ASPO, May 2016.

• PATENTS

Harbison RA, Li Y, Bly RA, Aghdasi N, Hannaford B, Moe KS, Houlton JJ. "Computer-Assisted Maxillary Reconstruction", 62/342,318, May 27, 2016, provisional patent.

Harbison RA, Li Y, Berens AM, Bly RA, Aghdasi N, Hannaford B, Moe KS. "Smart Surgical Navigation", 62/337,559, May 17, 2016, provisional patent.

2014 – 2015

• PUBLICATIONS

Jara SM, Benke JR, Lin SY, Ishman SL. The Association between Secondhand Smoke and Sleep-Disordered Breathing in Children: A Systematic Review. Laryngoscope. 2015 Jan;125(1):241-7.

Kirkham EM, Weaver EM. “A Review of Multiple Hypothesis Testing in the Otolaryngology Literature.” The Laryngoscope. Epub ahead of print. Aug 11, 2014.

Kuo CY, Parikh SR. Can lingual tonsillectomy improve persistent pediatric obstructive sleep apnea? Laryngoscope. 2014 Oct;124(10):2211-2.

Kuo CY, Parikh SR. Bacterial tracheitis. Pediatr Rev. 2014 Nov;35(11):497-9.

Mitchell RM, Horn DL. Case Report: Migration of a cochlear implant ground electrode through the calvarium of a pediatric patient. Int J Pediatr Otorhinolaryngol. 2015 Feb;79(2):278-80. Otorhinolaryngology. Accepted November 2014.

Purcell PL, Beck S, Davis GE. The Impact of Endoscopic Sinus Surgery on Total Direct Healthcare Costs Among Patients With Chronic Rhinosinusitis. Int Forum Allergy Rhinol. 2015 Jun;5(6):498-505.

Purcell PL, Shinn JR, Otto RK, Davis GE, Parikh SR. Nasoseptal Flap Reconstruction of Pediatric Sellar Defects: A Radiographic Feasiblity Study and Case Series. Otolaryngol Head Neck Surg. 2015 Apr;152(4):746-51.

Purcell P, Meyer T, Allen C. T.Tracheal Mass. Malignant Melanoma Metastatic to the Trachea.Jama Otolaryngol Head Neck Surgery. 2015 Mar;141(3):291-2

Shinn JR, Purcell PL, Horn DL, Sie KCY, Manning SC. First branchial cleft anomalies: Otologic manifestations and treatment outcomes. Otolaryngol Head Neck Surg. 2015 Mar;152(3):506-12.

Rawlani R, Rawlani V, Qureshi HA, Kim JY, Wayne JD. Reducing margins of wide local excision in head and neck melanoma for function and cosmesis: 5-year local recurrence-free survival., J Surg Oncol 2015 Jun; 111(7):795-9

Qureshi H, Ference E, Novis S, Pritchett CV, Smith SS, Schroeder JW. Trends in the management of pediatric peritonsillar abscess infections in the U.S., 2000-2009., Int. J. Pediatr. Otorhinolaryngol. 2015 Apr; 79(4):527-31

Qureshi HA, Ference EH, Tan BK, Chandra RK, Kern RC, Smith SS. National trends in retropharyngeal abscess among adult inpatients with peritonsillar abscess., Otolaryngol Head Neck Surg 2015 Apr; 152(4):661-6

Saxena RC, Scott AR. The varying presentations of type I laryngeal cleft: illustrative cases in a set of triplets., Int. J. Pediatr. Otorhinolaryngol. 2015 Apr; 79(4):620-2

Saxena RC, Lehmann AE, Hight AE, Darrow K, Remenschneider A, Kozin ED, Lee DJ. Social media utilization in the cochlear implant community., J Am Acad Audiol 2015 Feb; 26(2):197-204

O'Connell BP, Sood AJ, Gudis DA, Montiel M, White DR. Calcium Hydroxylapatite Injection for Persistent Velopharyngeal Insufficiency after Sphincter Pharyngoplasty., ORL J. Otorhinolaryngol. Relat. Spec. 2015 ; 77(3):155-61

Sood AJ, Houlton JJ, Nguyen SA, Gillespie MB. Facial nerve monitoring during parotidectomy: a systematic review and meta-analysis., Otolaryngol Head Neck Surg 2015 Apr; 152(4):631-7

Strüb GM, Perkins JA. Surgical management of head and neck malformations. Hemangiomas and Vascular Malformations: An Atlas of Diagnosis and Treatment. Mattassi R et al (eds.), Springer-Verlag Milan 2015.

Strüb GM, Parikh SR. Pediatric sinonasal anatomy and embryology. Sataloff’s Comprehensive Textbook of Otolaryngology, Hartnick: Pediatric Otolaryngology. JP Brothers Medical Publishers. November 2015.

• PRESENTATIONS

Baik FM, Inglis A, David GE. Pediatric Sublingual Hematoma from a Mandibular Fracture: Airway Management and Treatment Considerations. Triological Western Sections Meeting. 2015, January 22-24.

Kao M. Seattle Genetic Instability and Cancer Symposium, June 2015 -Fred Hutch Solid Tumor Translation Research Retreat, June 2015.

Mayerhoff RM, Kuo CY, Meyer, TK. A Novel Approach to the Challenging Injection Laryngoplasty Poster Presentation at Combined Otolaryngological Spring Meeting, American Broncho-Esophagological Association, Boston, MA, April 2015.

Lee VS, Gold RM, Parikh SR. Short-term quality of life outcomes after pediatric septoplasty. Podium presentation. The Triological Society, Combined Sections Meeting, Coronado, CA, January 22-24, 2015.

Lee VS, Evans KN, Perez FA, Oron AP, Perkins JA. Upper airway imaging measures that predict need for tracheotomy in children with Robin Sequence. Podium presentation. ASPO COSM, Boston, MA, April 22-26, 2015.

Purcell PL, Shinn JR, Davis GE, Otto R, Parikh SR. Nasoseptal flap reconstruction of pediatric sellar defects: A radiographic feasibility study. Podium presentation at the American Academy of Otolaryngology - Head & Neck Surgery annual meeting. Orlando, FL. Sept 2014.

Shinn JR, Purcell PL, Horn DL, Manning SC. First branchial cleft anomalies: Otologic manifestations and treatment outcomes. Podium presentation at the American Academy of Otolaryngology - Head & Neck Surgery annual meeting. Orlando, FL. Sept 2014.

• AWARDS

Berens A. Honor Your Physician Recipient. University of Washington Medical Center, Seattle, WA. 2014.

Berens AB, Li YM, Aghdasi N, Moe KS. Skull base planning software. UW Innovation Open House, Seattle, WA. October 2014.

Kirkham EM. American Academy of Otolaryngology Head & Neck Surgery Foundation (CORE Health Services Research) for project entitled: The Association Between Snoring and High-Risk Carotid Plaques: A Pilot Study. Project Period: 07/01/2014-6/30/2015.

2013 – 2014

• PUBLICATIONS

Bly RA, Ramakrishna R, Ferreira M, Moe KS. Lateral Transorbital Neuroendoscopic Approach to the Lateral Cavernous Sinus. J Neurol Surg: Skull Base. Accepted June 14, 2013.

Bly RA, Su D, Lendvay TS, Friedman D, Hannaford B, Ferreira M, Moe KS. Multiportal Robotic Access to the Anterior Cranial Fossa: A Surgical and Engineering Feasibility Study. Otolaryngol Head Neck Surg. Accepted Sep-27-2013.

Bly RA, Bly, EG. Consult Courtesy. Journal of Graduate Medical Education 5.3 (2013-September): 533-534.

Kuo CY, Wootten CT, Tylor DA, Werkhaven JA, Huffman KF, Goudy SL. Prevention of pressure ulcers after pediatric tracheotomy using a Mepilex Ag dressing. Laryngoscope. 2013 Jul 29.

Bledsoe TJ, Noble AR, Hunter GK, Rybicki LA, Hoschar A, Chute DJ, Saxton JP, Greskovich JF, Adelstein DJ, Koyfman SA. Oropharyngeal squamous cell carcinoma with known human papillomavirus status treated with definitive chemoradiotherapy: patterns of failure and toxicity outcomes. Radiat Oncol. 2013 Jul 9;8:174.

Purcell P, Meyer T, Allen C. Endoscopy case quiz: Tracheal Mass. JAMA Otolaryngol Head Neck Surg. Accepted June 2014.

Skirko JR, Weaver EM, Perkins JA, Kinter S, Ebien L, Sie KC. Validity and responsiveness of VELO: A velopharyngeal insufficiency quality of life measure. Otolaryngol Head Neck Surg. 2013 Aug;149(2):304-311.

Strub GM, Moore JE, Huang AT, Stevenson AW, Reiter ER. Chronic facial pain and Meckel cave masses as the initial presentation of neurosarcoidosis: a case report., Ear Nose Throat J 2013 Dec; 92(12):558-65

• PRESENTATIONS

Bly R. Multiportal robotic access to the anterior cranial fossa: A surgical and engineering feasibility study. Paper presented at the American Academy of Otolaryngology Head and Neck Surgery annual meeting, October 2013.

Bly R. Cricothyrotomy simulator with computational skill assessment for procedural skill training in the developing world. Paper presented at the American Academy of Otolaryngology Head and Neck Surgery annual meeting, October 2013.

Bly R. Tension pneumocephalus after endoscopic sinus surgery: A technical report of combined transorbital and transnasal multiportal repair using the “brain-sling” technique. Paper presented at the American Academy of Otolaryngology Head and Neck Surgery annual meeting, October 2013.

Bly R. Computer planning in the design of new skull base surgical approaches. Paper presented at the American Academy of Otolaryngology Head and Neck Surgery annual meeting, October 2013.

Bly RA. Computer Planning in the Research, Analysis and Design of Skull Base Surgical Approaches. Poster presentation at the American Academy of Otolaryngology-Head and Neck Surgery annual meeting. Vancouver, BC, Canada, September 2013.

Kirkham EM. Oral presentation: “The Association Between Clinical Outcome Measures and Apnea Hypopnea Index Corrected for CPAP Use”. June 4, 2014. SLEEP 2014. Minneapolis, Minnesota.

Kuo, CY. Pediatric Drug-Induced Sleep Endoscopy: Indications and Surgical Outcomes. Podium presentation at COSM annual meeting, May 2014.

Purcell PL, Iwata AJ, Phillips GS, Paladin AM, Sie KCY, Horn DL. Is bony cochlear nerve canal width related to word recognition score in pediatric patients with unilateral hearing loss? Poster presentation at the Combined Otolaryngology Society Meeting. Las Vegas, NV. May 2014.

Purcell PL, Beck S, Davis GE. Health care costs and antibiotic utilization following endoscopic surgery for chronic rhinosinusitis. Poster presentations at the Combined Otolaryngology Society Meeting. Las Vegas, NV. May 2014.

Strüb GM. MicroRNA mediated regression of infantile hemangioma by propranolol. International Society for the Study of Vascular Anomalies (ISSVA) Melbourne, Australia, April 2014.

• AWARDS

Bly R. Residency Travel Award for outstanding research paper, Computer-Guided Orbital Reconstruction to Improve Outcomes. American Academy of Facial Plastic and Reconstructive Surgery's Educational and Research Foundation, presented Oct 20, 2013, New Orleans, LA.

Bly R. Resident Leadership Grant Award. American Academy of Otolaryngology—Head and Neck Surgery. Presented September 29-October 2, 2013, Vancouver, BC, Canada.

Bly R. President Elect Award for outstanding poster presentation. Computer Planning in the Research, Analysis and Design of Skull Base Surgical Approaches. American Academy of Otolaryngology, Oct 2013, Vancouver, BC, Canada.

Bly R. Computer Modeled Multiportal Approaches to the Skull Base. American Academy of Otolaryngology Head and Neck Surgery Foundation Resident Research Grant ($9,735) 2013.

Bly R. Computer Modeled Multiportal Approaches to the Skull Base, NIH R21. Project Period: 09/01/2013 – 08/31/2015.

Kirkham E. American Society of Pediatric Otolaryngology and the Central Otolaryngology Research Effort (CORE) Study Section Grant for her project entitled: Assessment and validation of lymphatic malformation functional assessment. Presented at the American Academy of Otolaryngology Head and Neck Surgery annual meeting, October 2013.

Strüb GM. American Academy of Pediatric Otolaryngology (CORE) for project entitled: MicroRNA mediated regression of infantile hemangioma by propranolol ($20,000). Project Period: 06/2014-06/2015.

Strüb GM. MicroRNAs in infantile hemangioma. Exiqon Inc. Exiqon Grants Program ($12,500). 03/2014.

2012 – 2013

• PUBLICATIONS

Stein GY, Yosef N, Reichman H, Horev J, Laser-Azogui A, Berens A, Resau J, Ruppin E, Sharan R, Tsarfaty I. Met Kinetic Signature Derived from the Response to HGF/SF in a Cellular Model Predicts Breast Cancer Patient Survival. PLoS ONE 2012 Sept: 7(9).

Bly RA, Chang SH, Cudejkova M, Liu JJ, Moe KS. Computer-guided orbital reconstruction to improve outcomes. JAMA Facial Plast Surg. 2013 Mar 1;15(2):113-120.

Golub JS, Tong L, Ngyuen TB, Hume CR, Palmiter RD, Rubel EW, Stone JS. Hair cell replacement in adult mouse utricles after targeted ablation of hair cells with diphtheria toxin. J Neurosci. 2012 Oct 24;32(43):15093-15105.

Thomas AJ, Mong S, Golub JS, Meyer TK. Klebsiella pneumonia cervical necrotizing fasciitis originating as an abscess. Am J Otolaryngol. 2012 Nov-Dec;33(6):764-766.

Patel SA, Hillel AD, Perkins J. Battery ingestion leading to bilateral vocal cord paresis. JAMA Otolaryngol Head Neck Surg. 2013 Mar;139(3):304-306.

Patel S, Rudzinski E, Perkins J. Congenital neurocristic tumor of the head and neck. Laryngoscope. 2013 Mar;123(3):805-808.

Purcell P, Isaacson B, Oliver DH, Roland PS. Petros apex vascular malformation. Otol Neurotol. 2012 Oct;33(8):e67-68.

Boker A, Feetham HJ, Armstrong A, Purcell P, Jacobe H. Do automated text messages increase adherence to acne therapy? Results of a randomized, controlled trial. J Am Acad Dermatol. 2012 Dec;67(6):1136-1142.

Sharma A, Schwartz SM, Mendez E. Hospital volume is associated with survival but not multimodality therapy in Medicare patients with advanced head and neck cancer. Cancer. 2013 May 15;119(10):1845-1852.

Martins RG, Parvathaneni U, Bauman JE, Sharma AK, Raez LE, Papagilos MA, Yunus F, Kurland BF, Eaton KD, Liao JJ, Mendez E, Futran N, Wang DX, Chai X, Wallace SG, Austin M, Schmidt R, Hayes DN. Cisplatin and radiotherapy with or without erlotinib in locally advanced squamous cell carcinoma of the head and neck: A randomized phase II trial. J Clin Oncol. 2013 Apr 10;31(11):1415-1421.

Skirko JR, Weaver EM, Perkins J, Kinter S, Sie KC. Modification and evaluation of a velopharyngeal insufficiency quality-of-life instrument. Arch Otolaryngol Head Neck Surg. 2012 NIH R21NIH R21Oct;138(10):929-935.

Strub GM, Georgolios A, Graham RS, Powers CN, Coelho DH. Massive transcranial parotid pleomorphic adenoma: Recurrence after 30 years. J Neurol Surg Rep. 2012 Oct;73(1):1-5.

Strub GM, Moe KS. The use of negative-pressure therapy in the closure of complex head and neck wounds. Facial Plast Surg Clin North Am. 2013 Feb;21(1):137-145.

Bly RA. Computer-Guided Orbital Reconstruction to Improve Outcomes. Combined Otolaryngology Spring Meeting (COSM), Orlando, FL: April 2013.

• PRESENTATIONS

Bly RA. Transorbital Endoscopic Approach to the Lateral Cavernous Sinus. Poster presentation at the 23nd North American Skull Base Society Annual Meeting, Miami, FL, February 2013.

Liu J. The effect o nasal saline irrigation on olfaction: A prospective randomized trial. Poster presentation at the American Rhinological Association annual meeting, September 2012.

Patel S. Distribution of FDG PET & CT Imaging Results after Radiation. Poster presentation at the American Academy of Otolaryngology Head and Neck Surgery annual meeting, September 2012.

Patel S. Accuracy of FDG PET & CT imaging for nodal metastasis. Poster presentation at the American Academy of Otolaryngology Head and Neck Surgery annual meeting, September 2012.

Sharma A. The effect of hospital volume and designated cancer center status on treatment and survival in patients with advanced head and neck cancer. Paper presented at the 8th International Conference on Head and Neck Cancer, July 2012.

Skirko J. Validity and responsiveness of VELO: A VPI QOL instrument. Paper presented at the American Academy of Otolaryngology Head and Neck Surgery annual meeting, September 2012.

Skirko J. Allergic rhinitis and changing nasal congestion after CPAP. Paper presented at the American Academy of Otolaryngology Head and Neck Surgery annual meeting, September 2012.

• AWARDS

Bly R. The most outstanding clinical research presentation, presented by the American Academy of Facial Plastic and Reconstructive Surgery. Combined Otolaryngology Spring Meeting, Orlando, FL, April 2013.

Bly R. Computer Model for Advanced Pre-Operative Surgical Planning 2013 Coulter Foundation - Translational Research Grant ($100,000) 2013.

Levine C. Core Grant Recipient. American Academy of Otolaryngology – Head & Neck Surgery Foundation (AAO-HNSF), Olympus and the Centralized Otolaryngology Research Effort (CORE) Study Section Olympus/AAO-HNSF Resident Research Grant for grant proposal entitled Modification and Validation of a Quality of Life Comorbidity Index, September 2012.

Schmitt N. Core Grant Recipient. American Academy of Otolaryngology Head and Neck Surgery annual meeting, September 2012.

Sharma A. The effect of hospital volume and designated cancer center status on treatment and survival in patients with advanced head and neck cancer. American Head and Neck Society Robert Maxwell Byers Award for Best Clinical Research Paper. 8th International Conference on Head and Neck Cancer, July 2012.

Strüb GM, Perkins JA, Majesky MM. Propranolol induced changes in microRNAs expression in infantile hemangioma cells Seattle Children’s Hospital, Translational Research Ignition Projects Program ($100,000). 06/2013.

2011 – 2012

• PUBLICATIONS

Balakrishnan K, Majesky M, Perkins JA. Head and neck lymphatic tumors and bony abnormalities: A clinical and molecular review. Lymphat Res Biol. 2011(December);9(4):205-212.

Balakrishnan K, Edwards TC, Perkins JA. Functional and symptom impacts of pediatric head and neck lymphatic malformations: Developing a patient-derived instrument. Otolaryngology Head Neck Surg. 2012 Jun 6 [Epub ahead of print].

Bhama PK, Jordan D, Davis GE. Treatment of organized hematoma of the sphenoid sinus with pre-operative embolization and endoscopic resection. J Radiol. 2011 Dec;1:45-49.

Golub JS, Won JH, Drennan WR, Worman TD, Rubinstein JT. Spectral and temporal measures in hybrid cochlear implant users: on the mechanism of electroacoustic hearing benefits. Otol Neurotol. 2012; Feb;33(2):147-153.

Lin V, Golub J, Nguyen T, Hume CR, Oesterle EC, Stone JS. Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in adult mouse utricles. J Neurosci. 2011 Oct;31(43):15329-15339.

Zacharias C, Linnau KF, Golub JS, Meyer TK, Hecht AS, Mannelli L. Crack cocaine-induced supraglottitis. Emerg Radiol. 2011 Oct;18(5):445-447.

Hsia JC, Moe KS. Vacuum assisted therapy for reconstruction of soft tissue forehead defects. Arch Facial Plast. 2011; July-Aug13(4):278-282.

Harrington AT, Hsia JC, Méndez E, Clarridge JE. A lingual abscess caused by Streptococcus intermedius. J Med Microbiol. 2012 Apr;61(Pt4):590-592.

Lam DJChiu LL, Sie KC, Perkins J. Outcomes in palatoplasty: Impact of cleft width on the development of velopharyngeal insufficiency. Arch Facial Plast Surg 2012 Apr 16 [Epub ahead of print].

Lim JH, Davis GE, Rue T, Storm DR. Human sinonasal explant system for testing cytotoxicity of intranasal agents. Int Forum Allergy Rhinol. 2012 Jan-Feb;2 (1):63-68.

Lim J, Davis GE. Nasal and sinus surgery. In Golub J, Schmitt N (eds): Otolaryngology Surgical Instrument Guide. San Diego: Plural Publishing, Inc, 2012.

Chen EY, Lim JH, Boss EF, Inglis AF, Ou H, Sie K, Manning S, Perkins JA. Transoral approach for direct and complete excision of vallecular cysts in children. Int J Pediatr Otorhinolaryngol. 2011 Sept;75 (9) : 1147-1151.

Liu JJSharma A, Meyer TK. Laryngologic Surgery. In: Golub J, Schmitt N (eds). Otolaryngology Surgical Instrument Guide. San Diego, CA: Plural Publishing; 2011:155-205.

Sharma A, Mendez E, Yueh B, Lohavanichbutr P, Houck J, Doody DR, Futran ND, Upton MP, Schwartz SM, Chen C. Human papillomavirus-positive oral cavity and oropharyngeal cancer patients do not have better quality-of-life trajectories. Otolaryngol Head Neck Surg. 2012 May;146(5):739-745.

Bishehsari F, Sharma A, Stello K, Toth C, O’Connell MR, Evans AC, Larusch J, Muddana V, Papachristou GI, Whitcomb DC. TNF-alpha gene (TNFA) variants increase risk for multi-organ dysfunction syndrome (MODS) in acute pancreatitis. Pancreatology. 2012 Mar;12(2):113-118.

• PRESENTATIONS

Bhama P. The effects of intensive care unit staffing on patient outcomes following microvascular free flap reconstruction of the head and neck: A pilot study. Paper presented at the Combined Otolaryngology Spring Meetings, April 2012.

Bly R. Transorbital Robotic Skull Base Surgery: A Preclinical Study. Presented at Triological Society, Combined Sections Meeting, January 2012.

Bly R. Computer modeled multiportal approaches to the skull base. Paper presented at the 5th World Congress for Endoscopic Surgery of the Brain, Skull Base, and Spine, March 2012.

Golub J. Implantation of the vestibular system: Monkey and man. Paper presented at the American Otological Society meeting at the Combined Otolaryngology Spring Meetings, April 2012.

Golub J. Death and regeneration of vestibular hair cells in the Pou4f3-diphtheria toxin receptor mouse model. Poster presentation at the Association for Research in Otolaryngology annual meeting, February 2012.

Lim J. Human sinonasal explant system for testing cytotoxicity of intranasal agents. Paper presented at the American Rhinological Society Annual Meeting, September 2011.

Lim J. Transorbital neuroendoscopic management of sinogenic complications involving the frontal sinus, orbit and anterior cranial fossa. Poster presentation at the 22nd Annual North American Skull Base Society Meeting, February 2012.

Oxford R. Transorbital neuroendoscopic surgery of the middle cranial fossa by lateral retrocanthal approach. Poster presentation at the 22nd Annual North American Skull Base Society Meeting, February 2012.

Sharma A. HPV+ oral cancer patients do not have better QOL trajectory. Paper presented at the American Academy of Otolaryngology-Head and Neck Surgery Annual Meeting; September 2011.

Skirko JR. Reduction and validation of a velopharyngeal insufficiency Quality of Life instrument. Paper presented at the American Society of Pediatric Otolaryngology annual meeting (ASPO); April 2012.

Skirko JR. Development and validation of utility scoring for the SNORE-25 and FOSQ Quality of Life instruments. Paper presented at the Annual SLEEP meeting; June, 2012.

2010 – 2011

• PUBLICATIONS

Balakrishnan K, Moe KS. Applications and outcomes of orbital and transorbital endoscopic surgery. Otolaryngol Head Neck Surg. 2011 May;144(5):815-820.

Francis DO, Maynard C, Weymuller EA, Reiber G, Merati AL, Yueh B. Reevaluation of gastroesophageal reflux disease as a risk factor for laryngeal cancer. Laryngoscope. 2011(January);121(1):102-105.

Harbison RA, Ryan KR, Wilkins HM, Schroeder EK, Loucks FA, Bouchard RJ, Linseman DA. Calpain plays a central role in 1-methyl-4-phenylpyridinium (MPP+)-induced neurotoxicity in cerebellar granule neurons. Neurotox Res. 2011 Apr;19(3):374-88. doi: 10.1007/s12640-010-9172-4.