Jennifer Stone, Ph.D.
Jennifer Stone, Ph.D.
Biography
Dr. Stone received her graduate degree in anatomy and neurobiology from Boston University School of Medicine in 1993 and performed a post-doctoral fellowship at the University of Washington. In 1998, she became an assistant research professor in the Department of Otolaryngology-Head and Neck Surgery at the University of Washington. She was promoted to associate research professor in 2004 and to research professor in 2015. Since 2016 she has served as director of research for the department.
Overview
Undergraduate Education: Skidmore College, B.A. in Studio Art and Biology
Graduate Education: Boston University School of Medicine, Ph.D. in Anatomy and Neurobiology
Fellowship: University of Washington School of Medicine, Oto-HNS
Memberships: Association for Research in Otolaryngology (ARO), Society for Neuroscience
Awards and honors
Continuous NIH funding since 1998
Academic interests
RESEARCH FOCUS
The long-term goal of the Stone lab is to develop biologic therapies to help people with sensorineural hearing and balance disorders. They are investigating regeneration of sensory hair cells in adult mice. They are seeking new ways to promote functional recovery, in particular after hair cell destruction in vestibular organs. They are also working to understand how each of the two subtypes of hair cell develop and adopt their distinct functions in mammalian vestibular organs. They use mouse genetics, cellular imaging, gene expression studies, and organ culture methods to address these fundamental questions of inner ear biology.
Specific Publications
Stone JS, Pujol R, Nguyen TB, Cox BC. The transcription factor Sox2 is required to maintain the cell type-specific properties and innervation of type II vestibular hair cells in adult mice., J Neurosci 2021 Jun
Wan L, Lovett M, Warchol ME, Stone JS. Vascular endothelial growth factor is required for regeneration of auditory hair cells in the avian inner ear., Hear Res 2020 01; 385107839
Hicks KL, Wisner SR, Cox BC, Stone JS. Atoh1 is required in supporting cells for regeneration of vestibular hair cells in adult mice., Hear Res 2020 01; 385107838
Warchol ME, Massoodnia R, Pujol R, Cox BC, Stone JS. Development of hair cell phenotype and calyx nerve terminals in the neonatal mouse utricle., J Comp Neurol 2019 08; 527(11):1913-1928
Lab
Lab contact info
stoner@uw.edu
(206) 616-4108
Lab location
Virginia Merrill Bloedel Hearing Research Center
Box 357923, University of Washington
Seattle, WA 98195