"Throughout my medical and surgical training I was struck by the importance of normal fluid and cell transport. Over the past 20 years I have gravitated to the study and treatment of vascular anomalies, and I am motivated to discover how to control vessel growth in these anomalies so that we can offer more effective treatment and care to affected patients. It is exciting to live and practice medicine in a time when we have the biologic and genetic tools to make these treatments a reality."


Jonathan A. Perkins, D.O., is a professor of pediatric otolaryngology-head and neck surgery at the University of Washington and is chief of the Vascular Anomalies program at Seattle Children's Hospital. Perkins earned his D.O. at the University of Osteopathic Medicine and Health Sciences, did his residency training in otolaryngology at Madigan Army Medical Center in Fort Lewis, WA, and a pediatrics fellowship at Seattle Children's Hospital and the University of Washington.

While practicing all aspects of pediatric otolaryngology, his primary research interests are communication disorders and vascular anomalies of the head and neck. He serves as head of the Vascular Anomalies multidisciplinary service which is now the largest such service in the western United States. He also participates in the Craniofacial Center with a focus on palate repair. He practices at both the Bellevue and Sand Point campuses.


Undergraduate Education: Biola College, La Mirada, Cal., and University of Washington

Medical School: University of Osteopathic Medicine and Health Sciences, Des Moines, Iowa

Internship: Madigan Army Medical Center, Tacoma, Wash.

Residency: Surgery - General, Madigan Army Medical Center - Credentialing Office, Tacoma, Wash.

Fellowship: Pediatric Otolaryngology/Head and Neck Surgery Seattle Children's Hospital, Seattle, Wash.

Board Certification: Otolaryngology

Memberships: American Academy of Otolaryngology- Head and Neck Surgery, American Academy of Facial Plastic and Reconstructive Surgery

Awards and honors 

2015, 2009: Trachy Faculty Research Award, UW Otolaryngology-HNS
2015: Robert Ruben Award for Scientific Achievement, SENTAC
2013: Charles Ferguson Award 
2012: Washington Top Doctors
2009: Elsevier Publishing/Am Acad of Oto/HNS Foundation Travel Award
2007-present: Best Doctors of America 
Certificate of Honor, American Academy Oto/HNS

Academic interests 


Head and neck surgery, cleft palate treatment, velopharyngeal insufficiency, vascular birthmark treatment (lymphatic malformation, hemangioma, arteriovenous malformation), vascular/lymphatic endothelium research



Translational research and vascular anomalies


Recent Publications

Bonilla-Velez J, Whitlock KB, Ganti S, Shivaram GM, Bly RA, Dahl JP, Manning SC, Perkins JA. Delaying Invasive Treatment in Unilateral Head and Neck Lymphatic Malformation Improves Outcomes., Laryngoscope 2022 Jun

Zenner K, Jensen DM, Dmyterko V, Shivaram GM, Myers CT, Paschal CR, Rudzinski ER, Pham MM, Cheng VC, Manning SC, Bly RA, Ganti S, Perkins JA, Bennett JT. Somatic activating variants cause isolated lymphatic malformations., HGG Adv 2022 Apr; 3(2):100101

Pattisapu P, Wenger TL, Dahl JP, Bly RA, Bonilla-Velez J, Wu N, Hall A, Rudzinski ER, Perkins JA. Avoidance of surgery for head and neck infantile myofibromatosis using imatinib monotherapy., Clin Case Rep 2022 Feb; 10(2):e05382

Eysenbach LM, Koo KSH, Monroe EJ, Reis J, Perkins JA, Shivaram GM. Migration of n-BCA glue as a complication of venous malformation treatment in children., Radiol Case Rep 2021 Nov; 16(11):3526-3533

Bonilla-Velez J, Whitlock KB, Ganti S, Zenner K, Cheng CV, Jensen DM, Pham MM, Mitchell RM, Dobyns W, Bly RA, Bennett JT, Dahl JP, Perkins JA. Acetylsalicylic acid suppression of the PI3K pathway as a novel medical therapy for head and neck lymphatic malformations., Int J Pediatr Otorhinolaryngol 2021 Dec; 151110869


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