"I am fortunate to work among a fantastic group of investigators and clinicians, in an exhilarating research environment."

Biography 

Dr. Stone received her graduate degree in anatomy and neurobiology from Boston University School of Medicine in 1993 and performed a post-doctoral fellowship at the University of Washington. In 1998, she became an assistant research professor in the Department of Otolaryngology-Head and Neck Surgery at the University of Washington. She was promoted to associate research professor in 2004 and to research professor in 2015. Since 2016 she has served as director of research for the department. 

Overview 

Undergraduate Education: Skidmore College, B.A. in Studio Art and Biology

Graduate Education: Boston University School of Medicine, Ph.D. in Anatomy and Neurobiology

Fellowship: University of Washington School of Medicine, Oto-HNS

Memberships: Association for Research in Otolaryngology (ARO), Society for Neuroscience

Awards and honors 

Continuous NIH funding since 1998

Academic interests 

RESEARCH FOCUS

The long-term goal of the Stone lab is to develop biologic therapies to help people with sensorineural hearing and balance disorders. They are investigating regeneration of sensory hair cells in adult mice. They are seeking new ways to promote functional recovery, in particular after hair cell destruction in vestibular organs. They are also working to understand how each of the two subtypes of hair cell develop and adopt their distinct functions in mammalian vestibular organs. They use mouse genetics, cellular imaging, gene expression studies, and organ culture methods to address these fundamental questions of inner ear biology.

Specific Publications

González-Garrido A, Pujol R, López-Ramírez O, Finkbeiner C, Eatock RA, Stone JS. The Differentiation Status of Hair Cells That Regenerate Naturally in the Vestibular Inner Ear of the Adult Mouse., J Neurosci 2021 Sep; 41(37):7779-7796

Stone JS, Pujol R, Nguyen TB, Cox BC. The transcription factor Sox2 is required to maintain the cell type-specific properties and innervation of type II vestibular hair cells in adult mice., J Neurosci 2021 Jun

Wan L, Lovett M, Warchol ME, Stone JS. Vascular endothelial growth factor is required for regeneration of auditory hair cells in the avian inner ear., Hear Res 2020 01; 385107839

Hicks KL, Wisner SR, Cox BC, Stone JS. Atoh1 is required in supporting cells for regeneration of vestibular hair cells in adult mice., Hear Res 2020 01; 385107838

Warchol ME, Massoodnia R, Pujol R, Cox BC, Stone JS. Development of hair cell phenotype and calyx nerve terminals in the neonatal mouse utricle., J Comp Neurol 2019 08; 527(11):1913-1928

Lab 

Lab contact info 

stoner@uw.edu
(206) 616-4108

Lab location 

Virginia Merrill Bloedel Hearing Research Center
Box 357923, University of Washington
Seattle, WA 98195